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The Gut Advantage: 3 Ways HMOs Support Stronger Immunity and Smarter Kids

4 min read
The Gut Advantage: 3 Ways HMOs Support Stronger Immunity  and Smarter Kids

A healthy gut means a healthier, smarter child. Learn how HMOs support your child’s immunity, digestion, and learning—based on Abbott’s clinical research.

Children’s health is closely connected to their gut. With up to 70-80% of the immune system  located in the digestive tract, nurturing gut health early in life is one way to support a child’s overall growth, resilience, and learning potential. 

Children born via C-section may have differences in early microbial exposure, which can play a  role in gut and immune development.1 Advances in pediatric nutrition, including the addition of  human milk oligosaccharides (HMOs) in growing-up milk formulas, offer parents additional  options to help support their children’s health. 

A recent clinical study evaluated one of Abbott’s milk formulas containing a blend of 5 HMOs. In a large randomized controlled trial conducted in the U.S., researchers tracked more than 600  children for a full year. Results showed that formulas enriched with five HMOs can support gut  and immune health, brain development, normal growth and digestive tolerance.₂

Here’s how HMOs work to support children’s long-term health: 

  1. Nourish the “good” bacteria 

HMOs are specialized prebiotics that nourish beneficial bacteria in the gut and help these  bacteria thrive. This contributes to a healthier gut environment and supports digestive balance. For children born via C-section or those with sensitive tummies, formulas with HMOs may help  support a more balanced mix of good bacteria in the gut.₃

  1. Boost immunity from within 

Because much of the immune system is linked to the gut, supporting digestive health may also  support immune function. In the clinical study, children who consumed the formula with five HMOs experienced 40% fewer healthcare visits and an average of 3.4 fewer sick days compared  to children who did not receive the HMO-enriched formula.₂ These findings were observed within the study population and suggest a potential association between HMO supplementation  and immune-related outcomes. 

Dr. Elizabeth Reverri, nutrition scientist and registered dietitian at Abbott, explains, “Scientific  innovations have now made it possible to include multiple types of HMOs in pediatric  nutritional products to better reflect the diversity found in nature, supporting not just gut health but also immune and cognitive development.” 

  1. Support faster learning 

The gut and brain are closely connected, and when the digestive system is in balance, children are better able to absorb nutrients that fuel cognitive growth.  

In the same study, children consuming Abbott’s formula with five HMOs demonstrated stronger  language and social development. Specifically, 38% more of these children were able to imitate  words as they began to speak, and they understood 24% more everyday phrases compared to  those who did not receive formula containing five HMOs. These observed differences relate to  early communication behaviors that are considered important foundations for learning.₂

What this means for parents 

For parents looking for science-backed ways to support their child’s health, pediatric nutrition  products with five HMOs may be considered as part of a balanced diet. Abbott offers Similac  GainSchool and Similac Essencia+, specially formulated with five HMOs. 

Abbott has published over 65 studies on the benefits of HMOs, bringing advanced nutrition solutions to families who want to support their children’s gut health, immunity, and brain development. 

Dr. Reverri concludes, “A healthy gut lays the foundation for stronger immunity and cognitive development. With nutrition that includes HMOs—alongside balanced meals, active play, and  enough rest—parents can help their children grow up healthier, more resilient and ready to learn.” 

Note: Always consult your pediatrician before introducing new formulas or supplements to your child’s diet.

The Gut Advantage: 3 Ways HMOs Support Stronger Immunity  and Smarter KidsThe Gut Advantage: 3 Ways HMOs Support Stronger Immunity  and Smarter Kids

 

 

Similac GainSchool and Similac Essencia+ are specially formulated with five Human Milk Oligosaccharides (HMOs), prebiotics that help support children’s gut health, immunity, and brain development.

Similac® GainSchool and Similac Essencia®+ are now available in major supermarkets and drugstores nationwide and online at Lazada, Shopee and TikTok.

1 Amabebe, Emmanuel, Physiological Society Winter 2017: Does C-section impact on the early life
microbiome and immune system? doi.org/10.36866/pn.109.24

2 Presented at the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN);
further reference at Abbott Nutrition Health Institute: Randomized Clinical Trial in Infants Fed a Formula
Supplemented with 5 HMOs

3 Rousseaux A, Brosseau C, Le Gall S, Piloquet H, Barbarot S and Bodinier M (2021) Human Milk
Oligosaccharides: Their Effects on the Host and Their Potential as Therapeutic Agents. Front.
Immunol. 12:680911. doi: 10.3389/fimmu.2021.680911

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